Kisspeptin-10 (Metastin) 10mg — Dragon Pharma High-Purity Peptide
Enhance your laboratory research with Kisspeptin-10, a highly refined peptide designed for studying the HPG axis, metabolic regulation, and neuroprotective pathways. This Dragon Pharma formulation provides the precision and purity required for advanced biochemical and translational investigation.
Specifications
| Product Name | Kisspeptin-10 |
| Molecular Weight | 1302.4 g/mol |
| Molecular Formula | C₆₃H₈₃N₁₇O₁₄ |
| Sequence | YNWNSFGLRF (10 amino acids) |
| Size/Quantity | 10 mg |
| Form | Lyophilized powder |
| Purity히 | 99% |
| Storage Temperature | ≤ –20°C (long-term); 2–8°C (short-term) |
| PubChem CID | 25240297 |
| Other Designations | Kisspeptin 45–54, KISS-1, Metastin, Kp-10 peptide |
Description & Research Applications
Kisspeptin-10, also known as Metastin, is a bioactive peptide derived from the KISS1 gene. It serves as a critical ligand for the G-protein-coupled receptor GPR54 (KISS1R), playing a fundamental role in reproductive physiology and systemic homeostasis. This truncated fragment is highly effective in examining the hypothalamic-pituitary-gonadal (HPG) axis and its influence on reproductive hormone's secretion.
Beyond reproductive research, Kisspeptin-10 is a subject of intense study regarding energy balance, metabolic's role in appetite regulation, and cardiovascular health. Its ability to modulate neurotransmitters such as dopamine and serotonin makes it a valuable tool for research into mood, cognitive function, and neuroprotection. Additionally, its impact on protein's like alpha-synuclein provides significant insights into neurodegenerative research, particularly for models involving Parkinson's disease and dementia.
- Selective GPR54 Engagement: Potent activation of KISS1 receptor signaling at low nanomolar concentrations.
- Neuroprotective Potential: Demonstrates capacity to reduce neurotoxicity in cholinergic cellular models.
- Metabolic Regulation: Involved in the modulation of energy balance, appetite, and adipocyte activity.
- Cancer Research: Investigated for its role in suppressing metastasis and epithelial-mesenchymal transition.
- Versatile Application: Useful for studies in endocrinology, metabolic homeostasis, and neurobiology.
Shipping & Delivery
Please note the following shipping guidelines:
- Temporary shipping restrictions apply to Hawaii and Alaska.
- Military addresses (including APO, FPO, etc.) are currently not supported.
FAQ
What is Kisspeptin-10?
Kisspeptin-10 is a peptide used in research to study the regulatory mechanisms of the HPG axis. It functions by stimulating GnRH neurons, which in turn facilitates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). It is highly regarded in research for its ability to influence reproductive, metabolic, and even neuroprotective pathways.
How should this product be stored?
For long-term stability, the product should be stored at temperatures of ≤ –20°C. For short-term use, it can be maintained at 2–8°C. Always ensure the vial is handled according to standard laboratory protocols to maintain its 99% purity.