Kisspeptin-10 (Metastin) - 10mg High-Purity Research Peptide
Explore the biochemical potential of Kisspeptin-10, a highly bioactive peptide designed for advanced research into reproductive physiology and metabolic homeostasis. Whether investigating the hypothalamic-pituitary-gonadal (HPG) axis or metabolic' pathways, this precision-grade compound offers significant utility for scientific investigation.
Specifications
| Product Name | Kisspeptin-10 |
| Molecular Weight | 1302.4 g/mol |
| Molecular Formula | C₆₃H₈₃N₁₇O₁₄ |
| Sequence | YNWNSFGLRF (10 amino acids) |
| Purity | 99% |
| Form | Lyophilized powder |
| Storage Temperature | ≤ –20°C (long-term); 2–8°C (short-term) |
| PubChem CID | 25240297 |
Scientific Overview & Applications
Kisspeptin-10, also known as Metastin, is a bioactive peptide representing the C-10 sequence of the full-length Kisspeptin-54. It operates as a ligand for the G-protein-coupled receptor GPR54 (KISS1R), making it a critical mediator in reproductive hormone signaling. Despite its small size, this peptide exhibits profound biological influence, serving as a vital tool for studying the regulatory functions of the hypothalamus.
The versatility of this compound extends far beyond reproductive studies. Research highlights its role in:
- Metabolic Regulation: Modulating appetite, energy expenditure, and glucose tolerance through the regulation of food intake and energy's homeostasis.
- Neuroprotection: Demonstrating potential in reducing neurotoxicity by interacting with proteins like alpha-synuclein, which is vital for studying neurodegenerative conditions.
- Cardiovascular & Renal Function: Influencing renal vascular tone and assisting in the study of renal development and cardiovascular homeostasis.
- Oncology Research: Acting as a metastasis suppressor, potentially inhibiting the migration and invasion of various cancer cell lines.
This peptide is an essential instrument for researchers focusing on neurobiology, endocrinology, and metabolic' disorders. Its ability to influence neurotransmitter concentrations and mitochondrial function makes it a subject of significant interest in contemporary biochemical research.
Research Features
- Selective GPR54 Engagement: Potent and selective activation of the KISS1 receptor at low concentrations.
- Precision Neuroendocrine Modulation: Facilitates the study of GnRH and LH dynamics within the reproductive axis.
- Neuroprotective Potential: Shows activity in reducing neurotoxicity in cholinergic cellular models.
- Metabolic Versatility: Useful for investigating energy balance, appetite, and lipid metabolism.
- High Purity: Delivered as a 99% pure lyophilized powder for reliable results.
FAQ
What is Kisspe 10 (Metastin)?
Kisspeptin-10 is a peptide derived from the KISS1 gene that acts as a key regulator in reproductive physiology and systemic homeostasis through the GPR54 receptor.
What are the research applications for this peptide?
It is used in studies involving the HPG axis, metabolic rate regulation, appetite suppression, neuroprotection, and even potential anti-metastatic research in oncology.)
How should this product be stored?
For long-term stability, the product should be stored at temperatures of ≤ –20°C. Short-term use during active research should be maintained at 2–8°C.
Does this peptide affect appetite?
Yes, research indicates that Kisspeptin-10 modulates appetite and food intake by influencing hypothalamic nuclei and neurotransmitter concentrations.