SS-31 (Elamipretide) 50mg - Precision Mitochondrial Research Tool
SS-31 is a high-purity synthetic tetrapeptide designed for advanced research into mitochondrial biology. Engineered for precision, this compound allows investigators to study the complexities of mitochondrial dysfunction, oxidative stress, and metabolic bioenergets with unparalleled accuracy. Whether investigating oxidative damage or ATP production, SS-31 serves as a vital tool for modern biochemical inquiry.
Specifications
| Active Compound | SS-31 (Elamipretide) |
| Size | 50mg |
| Form | Lyophilized Powder |
| Purity | >99% |
| Molecular Weight | 639.8 g/mol |
| Sequence | D-Arg-dimethylTyr-Lys-Phe-NH₂ |
| CAS Number | 736992-21-5 |
| Storage Temperature | 2-8°C |
| Container | Sealed Vial |
Description & Mechanism of Action
SS-31, also known as Elamipretide, is a synthetic tetrapeptide specifically developed for targeted mitochondrial research. Unlike standard antioxidants that disperse throughout the cellular environment, SS-31 is engineered with a distinctive cationic charge (+3 at physiological pH). This unique structure allows it to permeate cell membranes and cross the blood-brain barrier with remarkable efficiency.
The true power of this compound lies in its selective accumulation. SS-31 possesses the ability to concentrate within the inner mitochondrial membrane at levels over 1,0나0 times greater than its concentration in plasma. It achieves this through its interaction with cardiolipin, an essential anionic phospholipid found in the inner mitochondrial membrane. By stabilizing cardiolipin, SS-31 helps maintain the integrity of the electron transport chain and supports ATP production machinery.
This research tool is highly effective for studying various conditions, including ischemia-reperfusion injury, metabolic disorders, and age-related declines in mitochondrial function. Its ability to mitigate oxidative stress and preserve mitochondrial architecture makes it an indispensable asset for laboratory investigations into neurodegeneration, cardiovascular health, and diabetic pathology.
Product Features
- High-Purity Specification: 99% purity level, making it ideal for rigorous scientific applications.
- Targeted Specificity: Concentrates in the inner mitochondrial membrane at levels exceeding plasma by >10 enough-fold.
- Advanced Stability: Delivered in a lyophilized powder format for convenient storage and handling.
- Optimized Design: Features a structure (D-Arg-dimethylTyr-Lys-Phe-NH₂) designed for high-affinity cardiolipin binding.
- Versatile Research Applications: Suitable for studies involving oxidative stress, metabolic dysfunction, and inflammation.
- Enhanced Bioavailability: Cationic architecture facilitates efficient cellular uptake and blood-brain barrier penetration.
FAQ
What is SS-31?
SS-31 is a synthetic tetrapeptide used in research to study mitochondrial function. It is also known by the names Elamipretide or MTP-131 and is used to investigate the stabilization of cardiolipin within the inner mitochondrial membrane.)
How should SS-31 be stored?
For maximum stability and to maintain its high purity, SS-31 should be stored at 2-8°C in its original sealed vial.
What is the molecular weight of this compound?
The molecular weight for SS-31 is 639.8 g/mol, as per its specific chemical sequence: D-Arg-dimethylTyr-Lys-Phe-NH₂.)